Liquid Cromatography Mass Spectroscopy (LC-MS)
LC/MS is a hyphenated technique, combining the separation power of HPLC, with the detection power of mass spectrometry. Even with a very sophisticated MS instrument, HPLC is still useful to remove the interferences from the sample that would impact the ionization.
Closely related to LC/MS are some other techniques, like flow injection/MS, CE or CEC/MS, capillary LC or nano LC/MS In all cases, there is the need for an interface that will eliminate the solvent and generate gas phase ions, then transferred to the optics of the mass spectrometer.
FF 23 + 24, Nathalal Estate, Near Canal, Behind M.H Marfatia, NH-8,opp Baroda Express Highway , Jashoda Chokdi, Ahmedabad, Gujarat, 380026, India